Wang, Pi-Lin <br/><br/>
Rac1 inhibition negatively regulates transcriptional activity of the amyloid precursor protein gene.  [electronic resource] 

 -  Journal of neuroscience research  Jul 2009 
 - 2105-14 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1097-4547 
<br/><br/><label>Standard No.: </label>10.1002/jnr.22039  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alzheimer Disease--genetics<br/>Aminoquinolines--pharmacology<br/>Amyloid beta-Peptides--metabolism<br/>Amyloid beta-Protein Precursor--biosynthesis<br/>Animals<br/>Cell Line<br/>Cells, Cultured<br/>Dose-Response Relationship, Drug<br/>Down-Regulation--drug effects<br/>Enzyme Inhibitors--pharmacology<br/>Gene Expression Regulation--drug effects<br/>Hippocampus--cytology<br/>Humans<br/>Mice<br/>Mice, Inbred ICR<br/>Neurons--drug effects<br/>Peptide Fragments--metabolism<br/>Promoter Regions, Genetic--genetics<br/>Proteasome Endopeptidase Complex--metabolism<br/>Proteasome Inhibitors<br/>Pyrimidines--pharmacology<br/>RNA, Messenger--drug effects<br/>RNA, Small Interfering--genetics<br/>Transcription, Genetic--drug effects<br/>Transfection<br/>rac1 GTP-Binding Protein--antagonists & inhibitors