TY - GEN AU - Rodríguez-Acebes,Sara AU - de la Cueva,Paloma AU - Fernández-Hernando,Carlos AU - Ferruelo,Antonio J AU - Lasunción,Miguel A AU - Rawson,Robert B AU - Martínez-Botas,Javier AU - Gómez-Coronado,Diego TI - Desmosterol can replace cholesterol in sustaining cell proliferation and regulating the SREBP pathway in a sterol-Delta24-reductase-deficient cell line SN - 1470-8728 PY - 2009///0609 KW - Animals KW - Blotting, Western KW - Cell Line KW - Cell Proliferation KW - drug effects KW - Cholesterol KW - metabolism KW - Chromatography, High Pressure Liquid KW - DNA-Binding Proteins KW - Desmosterol KW - HeLa Cells KW - Humans KW - Hydroxycholesterols KW - pharmacology KW - Hydroxymethylglutaryl-CoA Reductase Inhibitors KW - Liver X Receptors KW - Lovastatin KW - Macrophages KW - cytology KW - Mice KW - Nerve Tissue Proteins KW - deficiency KW - Orphan Nuclear Receptors KW - Oxidoreductases Acting on CH-CH Group Donors KW - RNA, Messenger KW - genetics KW - Receptors, Cytoplasmic and Nuclear KW - Reverse Transcriptase Polymerase Chain Reaction KW - Sterol Regulatory Element Binding Protein 1 KW - Sterol Regulatory Element Binding Protein 2 KW - Sterols KW - biosynthesis N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1042/BJ20081909 ER -