Perloff, E S <br/><br/>
Validation of cytochrome P450 time-dependent inhibition assays: a two-time point IC50 shift approach facilitates kinact assay design.  [electronic resource] 

 -  Xenobiotica; the fate of foreign compounds in biological systems  Feb 2009 
 - 99-112 p.  digital 
<br/><br/> Publication Type: Journal Article; Validation Study 
<br/><br/><label>ISSN: </label>1366-5928 
<br/><br/><label>Standard No.: </label>10.1080/00498250802638155  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Chromatography, Liquid<br/>Cytochrome P-450 Enzyme Inhibitors<br/>Drug Evaluation, Preclinical--methods<br/>Enzyme Inhibitors--pharmacology<br/>Humans<br/>Inhibitory Concentration 50<br/>Microsomes, Liver--drug effects<br/>Tandem Mass Spectrometry<br/>Time Factors