The integrin alpha2beta1 agonist, aggretin, promotes proliferation and migration of VSMC through NF-kB translocation and PDGF production. [electronic resource]
- British journal of pharmacology Mar 2009
- 846-56 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1476-5381
10.1111/j.1476-5381.2008.00095.x doi
Animals Becaplermin Cell Movement Cell Proliferation Cells, Cultured Enzyme Activation Extracellular Signal-Regulated MAP Kinases--metabolism Humans Integrin alpha2beta1--agonists Lectins, C-Type Muscle, Smooth, Vascular--cytology Myocytes, Smooth Muscle--cytology NF-kappa B--metabolism Phosphorylation Platelet-Derived Growth Factor--biosynthesis Protein Transport Proto-Oncogene Proteins c-sis Rats Receptor, Platelet-Derived Growth Factor beta--agonists Signal Transduction Type C Phospholipases--physiology Viper Venoms--pharmacology src-Family Kinases--metabolism