TY  - GEN
AU  - Jahangir,Alam
AU  - Alam,Muzaffar
AU  - Carter,David S
AU  - Dillon,Michael P
AU  - Bois,Daisy Joe Du
AU  - Ford,Anthony P D W
AU  - Gever,Joel R
AU  - Lin,Clara
AU  - Wagner,Paul J
AU  - Zhai,Yansheng
AU  - Zira,Jeff
TI  - Identification and SAR of novel diaminopyrimidines. Part 2: The discovery of RO-51, a potent and selective, dual P2X(3)/P2X(2/3) antagonist for the treatment of pain
SN  - 1464-3405
PY  - 2009///0820
KW  - Adenosine Triphosphate
KW  - chemistry
KW  - Analgesics
KW  - chemical synthesis
KW  - Animals
KW  - CHO Cells
KW  - Chemistry, Pharmaceutical
KW  - methods
KW  - Cricetinae
KW  - Cricetulus
KW  - Drug Design
KW  - Drug Evaluation, Preclinical
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Models, Chemical
KW  - Pain
KW  - drug therapy
KW  - Purinergic P2 Receptor Antagonists
KW  - Pyrimidines
KW  - Receptors, Purinergic P2
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2009.01.097
ER  -