Jahangir, Alam <br/><br/>
Identification and SAR of novel diaminopyrimidines. Part 2: The discovery of RO-51, a potent and selective, dual P2X(3)/P2X(2/3) antagonist for the treatment of pain.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Mar 2009 
 - 1632-5 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2009.01.097  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenosine Triphosphate--chemistry<br/>Analgesics--chemical synthesis<br/>Animals<br/>CHO Cells<br/>Chemistry, Pharmaceutical--methods<br/>Cricetinae<br/>Cricetulus<br/>Drug Design<br/>Drug Evaluation, Preclinical<br/>Humans<br/>Inhibitory Concentration 50<br/>Models, Chemical<br/>Pain--drug therapy<br/>Purinergic P2 Receptor Antagonists<br/>Pyrimidines--chemical synthesis<br/>Receptors, Purinergic P2--chemistry<br/>Structure-Activity Relationship