Cellular growth inhibition by FK778 is linked to G1 arrest or S phase accumulation, dependent on the functional status of the retinoblastoma protein. [electronic resource]
- International journal of molecular medicine Mar 2009
- 415-20 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1107-3756
10.3892/ijmm_00000146 doi
Alkynes--pharmacology Antiviral Agents--pharmacology DNA-Binding Proteins--biosynthesis G1 Phase--drug effects HeLa Cells Human papillomavirus 16--metabolism Human papillomavirus 18--metabolism Humans Isoxazoles--pharmacology Nitriles--pharmacology Oncogene Proteins, Viral--biosynthesis Papillomavirus E7 Proteins Phosphorylation--drug effects Retinoblastoma Protein--metabolism S Phase--drug effects Tumor Suppressor Protein p53--metabolism