TY - GEN AU - Doern,Adam AU - Cao,Xianjun AU - Sereno,Arlene AU - Reyes,Christopher L AU - Altshuler,Angelina AU - Huang,Flora AU - Hession,Cathy AU - Flavier,Albert AU - Favis,Michael AU - Tran,Hon AU - Ailor,Eric AU - Levesque,Melissa AU - Murphy,Tracey AU - Berquist,Lisa AU - Tamraz,Susan AU - Snipas,Tracey AU - Garber,Ellen AU - Shestowsky,William S AU - Rennard,Rachel AU - Graff,Christilyn P AU - Wu,Xiufeng AU - Snyder,William AU - Cole,Lindsay AU - Gregson,David AU - Shields,Michael AU - Ho,Steffan N AU - Reff,Mitchell E AU - Glaser,Scott M AU - Dong,Jianying AU - Demarest,Stephen J AU - Hariharan,Kandasamy TI - Characterization of inhibitory anti-insulin-like growth factor receptor antibodies with different epitope specificity and ligand-blocking properties: implications for mechanism of action in vivo SN - 0021-9258 PY - 2009///0520 KW - Allosteric Site KW - Animals KW - CHO Cells KW - Calorimetry, Differential Scanning KW - Cricetinae KW - Cricetulus KW - Epitope Mapping KW - Epitopes KW - chemistry KW - Humans KW - Insulin-Like Growth Factor II KW - Kinetics KW - Ligands KW - Molecular Conformation KW - Receptor, IGF Type 1 KW - metabolism KW - Receptors, Somatomedin N1 - Publication Type: Journal Article UR - https://doi.org/10.1074/jbc.M809709200 ER -