TY  - GEN
AU  - Zandvliet,Anthe S
AU  - Karlsson,Mats O
AU  - Schellens,Jan H M
AU  - Copalu,William
AU  - Beijnen,Jos H
AU  - Huitema,Alwin D R
TI  - Two-stage model-based clinical trial design to optimize phase I development of novel anticancer agents
SN  - 1573-0646
PY  - 2010///0323
KW  - Antineoplastic Agents
KW  - pharmacokinetics
KW  - Clinical Trials, Phase I as Topic
KW  - Computer Simulation
KW  - Dose-Response Relationship, Drug
KW  - Drug Design
KW  - Humans
KW  - Models, Statistical
KW  - Sulfonamides
KW  - administration & dosage
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1007/s10637-008-9216-2
ER  -