Zandvliet, Anthe S

Two-stage model-based clinical trial design to optimize phase I development of novel anticancer agents. [electronic resource] - Investigational new drugs Feb 2010 - 61-75 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1573-0646

10.1007/s10637-008-9216-2 doi


Antineoplastic Agents--pharmacokinetics
Clinical Trials, Phase I as Topic
Computer Simulation
Dose-Response Relationship, Drug
Drug Design
Humans
Models, Statistical
Sulfonamides--administration & dosage