Two-stage model-based clinical trial design to optimize phase I development of novel anticancer agents. [electronic resource]
- Investigational new drugs Feb 2010
- 61-75 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1573-0646
10.1007/s10637-008-9216-2 doi
Antineoplastic Agents--pharmacokinetics Clinical Trials, Phase I as Topic Computer Simulation Dose-Response Relationship, Drug Drug Design Humans Models, Statistical Sulfonamides--administration & dosage