TY  - GEN
AU  - Secchiero,Paola
AU  - Melloni,Elisabetta
AU  - di Iasio,Maria Grazia
AU  - Tiribelli,Mario
AU  - Rimondi,Erika
AU  - Corallini,Federica
AU  - Gattei,Valter
AU  - Zauli,Giorgio
TI  - Nutlin-3 up-regulates the expression of Notch1 in both myeloid and lymphoid leukemic cells, as part of a negative feedback antiapoptotic mechanism
SN  - 1528-0020
PY  - 2009///0602
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Amyloid Precursor Protein Secretases
KW  - antagonists & inhibitors
KW  - Apoptosis
KW  - Blotting, Western
KW  - Carbamates
KW  - pharmacology
KW  - Cell Differentiation
KW  - Dipeptides
KW  - Drug Synergism
KW  - Drug Therapy, Combination
KW  - Feedback, Physiological
KW  - Female
KW  - HL-60 Cells
KW  - Humans
KW  - Imidazoles
KW  - Leukemia, Lymphocytic, Chronic, B-Cell
KW  - genetics
KW  - Male
KW  - Middle Aged
KW  - Osteoclasts
KW  - cytology
KW  - Piperazines
KW  - RNA, Messenger
KW  - metabolism
KW  - Receptor, Notch1
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Stereoisomerism
KW  - Tumor Suppressor Protein p53
KW  - Up-Regulation
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1182/blood-2008-11-187708
ER  -