TY - GEN AU - Trédan,Olivier AU - Garbens,Alaina B AU - Lalani,Alshad S AU - Tannock,Ian F TI - The hypoxia-activated ProDrug AQ4N penetrates deeply in tumor tissues and complements the limited distribution of mitoxantrone SN - 1538-7445 PY - 2009///0323 KW - Animals KW - Anthraquinones KW - administration & dosage KW - Antineoplastic Combined Chemotherapy Protocols KW - pharmacokinetics KW - Cell Hypoxia KW - Humans KW - Male KW - Mice KW - Mitoxantrone KW - Neoplasms KW - drug therapy KW - Prodrugs KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/0008-5472.CAN-08-0676 ER -