Trédan, Olivier <br/><br/>
The hypoxia-activated ProDrug AQ4N penetrates deeply in tumor tissues and complements the limited distribution of mitoxantrone.  [electronic resource] 

 -  Cancer research  Feb 2009 
 - 940-7 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1538-7445 
<br/><br/><label>Standard No.: </label>10.1158/0008-5472.CAN-08-0676  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Anthraquinones--administration & dosage<br/>Antineoplastic Combined Chemotherapy Protocols--pharmacokinetics<br/>Cell Hypoxia<br/>Humans<br/>Male<br/>Mice<br/>Mitoxantrone--administration & dosage<br/>Neoplasms--drug therapy<br/>Prodrugs--administration & dosage<br/>Xenograft Model Antitumor Assays