TY - GEN AU - Marwick,John A AU - Caramori,Gaetano AU - Stevenson,Christopher S AU - Casolari,Paolo AU - Jazrawi,Elen AU - Barnes,Peter J AU - Ito,Kazuhiro AU - Adcock,Ian M AU - Kirkham,Paul A AU - Papi,Alberto TI - Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice SN - 1535-4970 PY - 2009///0428 KW - Administration, Inhalation KW - Aged KW - Animals KW - Case-Control Studies KW - Cells, Cultured KW - Class I Phosphatidylinositol 3-Kinases KW - Drug Resistance KW - Female KW - Glucocorticoids KW - administration & dosage KW - Histone Deacetylase 2 KW - Histone Deacetylases KW - drug effects KW - Humans KW - Male KW - Mice KW - Mice, Transgenic KW - Oxidative Stress KW - Phosphatidylinositol 3-Kinases KW - physiology KW - Phosphoinositide-3 Kinase Inhibitors KW - Pulmonary Disease, Chronic Obstructive KW - drug therapy KW - Receptors, Glucocorticoid KW - Repressor Proteins KW - Smoking KW - adverse effects N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1164/rccm.200810-1570OC ER -