Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy. [electronic resource]
- Journal of clinical oncology : official journal of the American Society of Clinical Oncology Feb 2009
- 857-71 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1527-7755
10.1200/JCO.2008.17.6297 doi
Adult Aged Antineoplastic Agents--therapeutic use Carrier Proteins--genetics Class I Phosphatidylinositol 3-Kinases Esophageal Neoplasms--genetics Female Genotype Humans Male Middle Aged PTEN Phosphohydrolase--genetics Phosphatidylinositol 3-Kinases--genetics Phosphotransferases (Alcohol Group Acceptor)--genetics Polymorphism, Single Nucleotide Proto-Oncogene Proteins c-akt--genetics Radiotherapy Signal Transduction--genetics TOR Serine-Threonine Kinases Treatment Outcome