Ggamma1, a downstream target for the hmgcr-isoprenoid biosynthetic pathway, is required for releasing the Hedgehog ligand and directing germ cell migration. [electronic resource]
- PLoS genetics Jan 2009
- e1000333 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1553-7404
10.1371/journal.pgen.1000333 doi
Animals Animals, Genetically Modified Cell Movement Dimethylallyltranstransferase--genetics Drosophila--cytology Drosophila Proteins--genetics Farnesyltranstransferase--genetics Female GTP-Binding Protein gamma Subunits--genetics Germ Cells--physiology Hedgehog Proteins--genetics Hydroxymethylglutaryl CoA Reductases--genetics Male Metabolic Networks and Pathways--genetics Mevalonic Acid--metabolism Mutation Protein Processing, Post-Translational--genetics Receptors, G-Protein-Coupled--genetics Smoothened Receptor Terpenes--metabolism Wings, Animal--anatomy & histology