Bane, Fiona T <br/><br/>
The microtubule-targeting agents, PBOX-6 [pyrrolobenzoxazepine 7-[(dimethylcarbamoyl)oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine] and paclitaxel, induce nucleocytoplasmic redistribution of the peptidyl-prolyl isomerases, cyclophilin A and pin1, in malignant hematopoietic cells.  [electronic resource] 

 -  The Journal of pharmacology and experimental therapeutics  Apr 2009 
 - 38-47 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1521-0103 
<br/><br/><label>Standard No.: </label>10.1124/jpet.108.148130  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents, Phytogenic--pharmacology<br/>Blotting, Western<br/>Cell Division--drug effects<br/>Cell Membrane--drug effects<br/>Cell Nucleus--drug effects<br/>Cyclophilin A--metabolism<br/>Cytoplasm--drug effects<br/>Electrophoresis, Polyacrylamide Gel<br/>Flow Cytometry<br/>G2 Phase--drug effects<br/>Hematologic Neoplasms--metabolism<br/>Humans<br/>Hydrolysis<br/>Microtubules--drug effects<br/>Monocytes--drug effects<br/>NIMA-Interacting Peptidylprolyl Isomerase<br/>Oxazepines--pharmacology<br/>Paclitaxel--pharmacology<br/>Peptide Mapping<br/>Peptidylprolyl Isomerase--metabolism<br/>Pyrroles--pharmacology<br/>Silver Staining<br/>Trypsin--chemistry