PTEN and rapamycin inhibiting the growth of K562 cells through regulating mTOR signaling pathway. [electronic resource]
- Journal of experimental & clinical cancer research : CR Dec 2008
- 87 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1756-9966
10.1186/1756-9966-27-87 doi
Apoptosis--drug effects Cell Growth Processes--drug effects Cell Line, Tumor Cyclin D1--biosynthesis Cyclin-Dependent Kinase Inhibitor p27 Gene Expression Regulation, Neoplastic Humans Intracellular Signaling Peptides and Proteins--genetics K562 Cells PTEN Phosphohydrolase--biosynthesis Protein Kinases--biosynthesis RNA, Messenger--biosynthesis Signal Transduction Sirolimus--metabolism TOR Serine-Threonine Kinases Transfection