TY - GEN AU - Ji,Hong-Long AU - Song,Weifeng AU - Gao,Zhiqian AU - Su,Xue-Feng AU - Nie,Hong-Guang AU - Jiang,Yi AU - Peng,Ji-Bin AU - He,Yu-Xian AU - Liao,Ying AU - Zhou,Yong-Jian AU - Tousson,Albert AU - Matalon,Sadis TI - SARS-CoV proteins decrease levels and activity of human ENaC via activation of distinct PKC isoforms SN - 1040-0605 PY - 2009///0414 KW - Acute Lung Injury KW - etiology KW - Amiloride KW - pharmacology KW - Animals KW - Cell Line KW - Endocytosis KW - Enzyme Activation KW - Epithelial Sodium Channels KW - genetics KW - Exocytosis KW - Female KW - Gene Expression KW - Humans KW - In Vitro Techniques KW - Isoenzymes KW - antagonists & inhibitors KW - Membrane Glycoproteins KW - Oocytes KW - metabolism KW - Patch-Clamp Techniques KW - Protein Kinase C KW - Protein Kinase Inhibitors KW - Pulmonary Edema KW - Recombinant Proteins KW - Severe acute respiratory syndrome-related coronavirus KW - Spike Glycoprotein, Coronavirus KW - Transfection KW - Viral Envelope Proteins KW - Viral Proteins KW - Viroporin Proteins KW - Xenopus N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1152/ajplung.90437.2008 ER -