TY - GEN AU - Zimmer,Michael AU - Ebert,Benjamin L AU - Neil,Christopher AU - Brenner,Keith AU - Papaioannou,Ioannis AU - Melas,Antonia AU - Tolliday,Nicola AU - Lamb,Justin AU - Pantopoulos,Kostas AU - Golub,Todd AU - Iliopoulos,Othon TI - Small-molecule inhibitors of HIF-2a translation link its 5'UTR iron-responsive element to oxygen sensing SN - 1097-4164 PY - 2009///0123 KW - 5' Untranslated Regions KW - genetics KW - Basic Helix-Loop-Helix Transcription Factors KW - biosynthesis KW - Cell Hypoxia KW - drug effects KW - Cell Proliferation KW - Culture Media, Conditioned KW - Dose-Response Relationship, Drug KW - Endothelial Cells KW - cytology KW - Gene Expression Profiling KW - Gene Expression Regulation KW - Humans KW - Iron KW - metabolism KW - Iron Chelating Agents KW - pharmacology KW - Iron-Regulatory Proteins KW - Oxygen KW - Protein Binding KW - Protein Biosynthesis KW - Protein Kinases KW - Protein Stability KW - RNA Stability KW - RNA, Messenger KW - Receptors, Transferrin KW - Response Elements KW - Small Molecule Libraries KW - analysis KW - TOR Serine-Threonine Kinases N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.molcel.2008.12.004 ER -