TY - GEN AU - Shan,Yibing AU - Seeliger,Markus A AU - Eastwood,Michael P AU - Frank,Filipp AU - Xu,Huafeng AU - Jensen,Morten Ø AU - Dror,Ron O AU - Kuriyan,John AU - Shaw,David E TI - A conserved protonation-dependent switch controls drug binding in the Abl kinase SN - 1091-6490 PY - 2009///0213 KW - Amino Acid Motifs KW - Aspartic Acid KW - Catalysis KW - Computer Simulation KW - Hydrogen-Ion Concentration KW - Kinetics KW - Models, Molecular KW - Pharmaceutical Preparations KW - chemistry KW - Protein Binding KW - Protein Conformation KW - Proto-Oncogene Proteins c-abl KW - Static Electricity N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1073/pnas.0811223106 ER -