TY  - GEN
AU  - Valdmanis,Paul N
AU  - Verlaan,Dominique J
AU  - Rouleau,Guy A
TI  - The proportion of mutations predicted to have a deleterious effect differs between gain and loss of function genes in neurodegenerative disease
SN  - 1098-1004
PY  - 2009///0528
KW  - Adenosine Triphosphatases
KW  - genetics
KW  - Amino Acid Substitution
KW  - Amyloid beta-Protein Precursor
KW  - Computational Biology
KW  - methods
KW  - GTP Phosphohydrolases
KW  - GTP-Binding Proteins
KW  - Genetic Predisposition to Disease
KW  - Humans
KW  - Membrane Proteins
KW  - Mutation
KW  - Neurodegenerative Diseases
KW  - Presenilin-1
KW  - Software
KW  - Spastin
KW  - Superoxide Dismutase
KW  - Superoxide Dismutase-1
KW  - Survival of Motor Neuron 1 Protein
KW  - Ubiquitin-Protein Ligases
KW  - tau Proteins
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1002/humu.20939
ER  -