TY  - GEN
AU  - Liu,Wei Wei
AU  - Todd,Stephen
AU  - Coulson,David T R
AU  - Irvine,G Brent
AU  - Passmore,A Peter
AU  - McGuinness,Bernadette
AU  - McConville,Maeve
AU  - Craig,David
AU  - Johnston,Janet A
TI  - A novel reciprocal and biphasic relationship between membrane cholesterol and beta-secretase activity in SH-SY5Y cells and in human platelets
SN  - 1471-4159
PY  - 2009///0408
KW  - Aged
KW  - Aged, 80 and over
KW  - Alzheimer Disease
KW  - blood
KW  - Amyloid Precursor Protein Secretases
KW  - antagonists & inhibitors
KW  - Aspartic Acid Endopeptidases
KW  - metabolism
KW  - Blood Platelets
KW  - cytology
KW  - Case-Control Studies
KW  - Cell Line, Tumor
KW  - Cell Membrane
KW  - drug effects
KW  - Cholesterol
KW  - Cognition Disorders
KW  - Culture Media, Serum-Free
KW  - pharmacology
KW  - Dose-Response Relationship, Drug
KW  - Enzyme Inhibitors
KW  - Enzyme-Linked Immunosorbent Assay
KW  - methods
KW  - Female
KW  - Humans
KW  - Hydroxymethylglutaryl-CoA Reductase Inhibitors
KW  - Linear Models
KW  - Male
KW  - Neuroblastoma
KW  - pathology
KW  - Statistics, Nonparametric
KW  - Subcellular Fractions
KW  - Time Factors
KW  - beta-Cyclodextrins
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1111/j.1471-4159.2008.05753.x
ER  -