Liu, Wei Wei

A novel reciprocal and biphasic relationship between membrane cholesterol and beta-secretase activity in SH-SY5Y cells and in human platelets. [electronic resource] - Journal of neurochemistry Jan 2009 - 341-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1471-4159

10.1111/j.1471-4159.2008.05753.x doi


Aged
Aged, 80 and over
Alzheimer Disease--blood
Amyloid Precursor Protein Secretases--antagonists & inhibitors
Aspartic Acid Endopeptidases--metabolism
Blood Platelets--cytology
Case-Control Studies
Cell Line, Tumor
Cell Membrane--drug effects
Cholesterol--metabolism
Cognition Disorders--blood
Culture Media, Serum-Free--pharmacology
Dose-Response Relationship, Drug
Enzyme Inhibitors
Enzyme-Linked Immunosorbent Assay--methods
Female
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology
Linear Models
Male
Neuroblastoma--pathology
Statistics, Nonparametric
Subcellular Fractions
Time Factors
beta-Cyclodextrins--pharmacology