TY - GEN AU - Terao,S AU - Ohkawa,S AU - Terashita,Z AU - Shibouta,Y AU - Nishikawa,K TI - Synthesis and biological evaluation of 2,3,5-trimethyl-6-(3-pyridylmethyl)-1,4-benzoquinone (CV-6504), a dual inhibitor of TXA2 synthase and 5-lipoxygenase with scavenging activity of active oxygen species (AOS) SN - 0732-8141 PY - 1991///0403 KW - 6-Ketoprostaglandin F1 alpha KW - biosynthesis KW - Animals KW - Antioxidants KW - chemical synthesis KW - Benzoquinones KW - Drug Design KW - Drug Evaluation, Preclinical KW - Free Radicals KW - Glomerulonephritis KW - chemically induced KW - Humans KW - Leukotriene B4 KW - Lipoxygenase Inhibitors KW - Molecular Structure KW - Oxygen KW - metabolism KW - Puromycin Aminonucleoside KW - toxicity KW - Rats KW - Structure-Activity Relationship KW - Thromboxane B2 KW - Thromboxane-A Synthase KW - antagonists & inhibitors N1 - Publication Type: Journal Article ER -