TY - GEN AU - Sernández,Isora V AU - de Yébenes,Virginia G AU - Dorsett,Yair AU - Ramiro,Almudena R TI - Haploinsufficiency of activation-induced deaminase for antibody diversification and chromosome translocations both in vitro and in vivo SN - 1932-6203 PY - 2009///0223 KW - Animals KW - Antibody Diversity KW - genetics KW - B-Lymphocytes KW - enzymology KW - Chromosomes, Mammalian KW - Cytidine Deaminase KW - Haploidy KW - Hyperplasia KW - Immunoglobulin Class Switching KW - Immunoglobulin Heavy Chains KW - Interleukin-6 KW - immunology KW - Lymph Nodes KW - Lymphocyte Activation KW - Mice KW - Mice, Transgenic KW - Proto-Oncogene Proteins c-myc KW - Recombination, Genetic KW - Somatic Hypermutation, Immunoglobulin KW - Translocation, Genetic KW - AICDA (Activation-Induced Cytidine Deaminase) N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0003927 ER -