TY  - GEN
AU  - Lim,Yun-Ping
AU  - Kuo,Sheng-Chun
AU  - Lai,Ming-Liang
AU  - Huang,Jin-Ding
TI  - Inhibition of CYP3A4 expression by ketoconazole is mediated by the disruption of pregnane X receptor, steroid receptor coactivator-1, and hepatocyte nuclear factor 4alpha interaction
SN  - 1744-6872
PY  - 2009///0303
KW  - Antifungal Agents
KW  - pharmacology
KW  - Base Sequence
KW  - Cell Line
KW  - Cytochrome P-450 CYP3A
KW  - genetics
KW  - Cytochrome P-450 CYP3A Inhibitors
KW  - DNA Primers
KW  - Gene Expression Regulation, Enzymologic
KW  - drug effects
KW  - HeLa Cells
KW  - Hepatocyte Nuclear Factor 4
KW  - antagonists & inhibitors
KW  - Histone Acetyltransferases
KW  - Humans
KW  - In Vitro Techniques
KW  - Ketoconazole
KW  - Ligands
KW  - Nuclear Receptor Coactivator 1
KW  - Pharmacogenetics
KW  - Pregnane X Receptor
KW  - Promoter Regions, Genetic
KW  - Protein Interaction Domains and Motifs
KW  - RNA Interference
KW  - Receptors, Steroid
KW  - Recombinant Proteins
KW  - Rifampin
KW  - Transcription Factors
KW  - Two-Hybrid System Techniques
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1097/FPC.0b013e32831665ea
ER  -