Lim, Yun-Ping <br/><br/>
Inhibition of CYP3A4 expression by ketoconazole is mediated by the disruption of pregnane X receptor, steroid receptor coactivator-1, and hepatocyte nuclear factor 4alpha interaction.  [electronic resource] 

 -  Pharmacogenetics and genomics  Jan 2009 
 - 11-24 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1744-6872 
<br/><br/><label>Standard No.: </label>10.1097/FPC.0b013e32831665ea  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antifungal Agents--pharmacology<br/>Base Sequence<br/>Cell Line<br/>Cytochrome P-450 CYP3A--genetics<br/>Cytochrome P-450 CYP3A Inhibitors<br/>DNA Primers--genetics<br/>Gene Expression Regulation, Enzymologic--drug effects<br/>HeLa Cells<br/>Hepatocyte Nuclear Factor 4--antagonists & inhibitors<br/>Histone Acetyltransferases--antagonists & inhibitors<br/>Humans<br/>In Vitro Techniques<br/>Ketoconazole--pharmacology<br/>Ligands<br/>Nuclear Receptor Coactivator 1<br/>Pharmacogenetics<br/>Pregnane X Receptor<br/>Promoter Regions, Genetic<br/>Protein Interaction Domains and Motifs<br/>RNA Interference<br/>Receptors, Steroid--antagonists & inhibitors<br/>Recombinant Proteins--antagonists & inhibitors<br/>Rifampin--pharmacology<br/>Transcription Factors--antagonists & inhibitors<br/>Two-Hybrid System Techniques