TY  - GEN
AU  - Bolognese,Adele
AU  - Correale,Gaetano
AU  - Manfra,Michele
AU  - Esposito,Anna
AU  - Novellino,Ettore
AU  - Lavecchia,Antonio
TI  - Antitumor agents 6. Synthesis, structure-activity relationships, and biological evaluation of spiro[imidazolidine-4,3'-thieno[2,3-g]quinoline]-tetraones and spiro[thieno[2,3-g]quinoline-3,5'-[1,2,4]triazinane]-tetraones with potent antiproliferative activity
SN  - 1520-4804
PY  - 2009///0122
KW  - Antineoplastic Agents
KW  - chemical synthesis
KW  - Catalysis
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Chemistry, Pharmaceutical
KW  - methods
KW  - DNA
KW  - chemistry
KW  - Drug Design
KW  - Drug Screening Assays, Antitumor
KW  - Enzyme Inhibitors
KW  - pharmacology
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Neoplasms
KW  - drug therapy
KW  - Quinolines
KW  - Structure-Activity Relationship
KW  - Topoisomerase II Inhibitors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/jm8007689
ER  -