Bolognese, Adele <br/><br/>
Antitumor agents 6. Synthesis, structure-activity relationships, and biological evaluation of spiro[imidazolidine-4,3'-thieno[2,3-g]quinoline]-tetraones and spiro[thieno[2,3-g]quinoline-3,5'-[1,2,4]triazinane]-tetraones with potent antiproliferative activity.  [electronic resource] 

 -  Journal of medicinal chemistry  Dec 2008 
 - 8148-57 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm8007689  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--chemical synthesis<br/>Catalysis<br/>Cell Line, Tumor<br/>Cell Proliferation<br/>Chemistry, Pharmaceutical--methods<br/>DNA--chemistry<br/>Drug Design<br/>Drug Screening Assays, Antitumor<br/>Enzyme Inhibitors--pharmacology<br/>Humans<br/>Inhibitory Concentration 50<br/>Neoplasms--drug therapy<br/>Quinolines--chemical synthesis<br/>Structure-Activity Relationship<br/>Topoisomerase II Inhibitors