TY  - GEN
AU  - Billamboz,Muriel
AU  - Bailly,Fabrice
AU  - Barreca,Maria Letizia
AU  - De Luca,Laura
AU  - Mouscadet,Jean-François
AU  - Calmels,Christina
AU  - Andréola,Marie-Line
AU  - Witvrouw,Myriam
AU  - Christ,Frauke
AU  - Debyser,Zeger
AU  - Cotelle,Philippe
TI  - Design, synthesis, and biological evaluation of a series of 2-hydroxyisoquinoline-1,3(2H,4H)-diones as dual inhibitors of human immunodeficiency virus type 1 integrase and the reverse transcriptase RNase H domain
SN  - 1520-4804
PY  - 2009///0122
KW  - Antiviral Agents
KW  - chemistry
KW  - Catalysis
KW  - Catalytic Domain
KW  - Cell Line
KW  - Chemistry, Pharmaceutical
KW  - methods
KW  - Drug Design
KW  - HIV-1
KW  - enzymology
KW  - Humans
KW  - Hydrogen Bonding
KW  - Inhibitory Concentration 50
KW  - Isoquinolines
KW  - pharmacology
KW  - Models, Chemical
KW  - Reverse Transcriptase Inhibitors
KW  - Ribonuclease H
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/jm8007085
ER  -