Billamboz, Muriel <br/><br/>
Design, synthesis, and biological evaluation of a series of 2-hydroxyisoquinoline-1,3(2H,4H)-diones as dual inhibitors of human immunodeficiency virus type 1 integrase and the reverse transcriptase RNase H domain.  [electronic resource] 

 -  Journal of medicinal chemistry  Dec 2008 
 - 7717-30 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm8007085  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antiviral Agents--chemistry<br/>Catalysis<br/>Catalytic Domain<br/>Cell Line<br/>Chemistry, Pharmaceutical--methods<br/>Drug Design<br/>HIV-1--enzymology<br/>Humans<br/>Hydrogen Bonding<br/>Inhibitory Concentration 50<br/>Isoquinolines--pharmacology<br/>Models, Chemical<br/>Reverse Transcriptase Inhibitors--chemistry<br/>Ribonuclease H--chemistry