The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner. [electronic resource]
- Molecular and cellular biology Feb 2009
- 640-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1098-5549
10.1128/MCB.00980-08 doi
Animals Carrier Proteins--metabolism Cell Line Cell Proliferation--drug effects Gene Expression Regulation--drug effects Humans Insulin--pharmacology Mice Mitosis--drug effects Monomeric GTP-Binding Proteins--metabolism Neuropeptides--metabolism Protein Biosynthesis--drug effects Protein Kinases--deficiency RNA 5' Terminal Oligopyrimidine Sequence--genetics Rapamycin-Insensitive Companion of mTOR Protein Ras Homolog Enriched in Brain Protein Sirolimus--pharmacology TOR Serine-Threonine Kinases Tacrolimus Binding Protein 1A--metabolism Tuberous Sclerosis Complex 1 Protein Tuberous Sclerosis Complex 2 Protein Tumor Suppressor Proteins--deficiency