TY - GEN AU - Oberdoerffer,Philipp AU - Michan,Shaday AU - McVay,Michael AU - Mostoslavsky,Raul AU - Vann,James AU - Park,Sang-Kyu AU - Hartlerode,Andrea AU - Stegmuller,Judith AU - Hafner,Angela AU - Loerch,Patrick AU - Wright,Sarah M AU - Mills,Kevin D AU - Bonni,Azad AU - Yankner,Bruce A AU - Scully,Ralph AU - Prolla,Tomas A AU - Alt,Frederick W AU - Sinclair,David A TI - SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging SN - 1097-4172 PY - 2008///1219 KW - Aging KW - genetics KW - Animals KW - Brain KW - metabolism KW - Cell Line, Tumor KW - Chromatin KW - DNA Breaks, Double-Stranded KW - DNA Repair KW - Embryonic Stem Cells KW - Gene Knockout Techniques KW - Genomic Instability KW - Humans KW - Lymphoma KW - Mice KW - Molecular Sequence Data KW - Oxidative Stress KW - Sirtuin 1 KW - Sirtuins KW - Specific Pathogen-Free Organisms KW - Thymus Neoplasms KW - Yeasts KW - cytology N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.cell.2008.10.025 ER -