TY - GEN AU - Giugliani,Roberto AU - Rojas,Verónica Muñoz AU - Martins,Ana Maria AU - Valadares,Eugênia R AU - Clarke,Joe T R AU - Góes,José E C AU - Kakkis,Emil D AU - Worden,Mary Alice AU - Sidman,Marisa AU - Cox,Gerald F TI - A dose-optimization trial of laronidase (Aldurazyme) in patients with mucopolysaccharidosis I SN - 1096-7206 PY - 2009///0121 KW - Adolescent KW - Child KW - Child, Preschool KW - Dose-Response Relationship, Drug KW - Drug Administration Schedule KW - Female KW - Glycosaminoglycans KW - urine KW - Humans KW - Iduronidase KW - administration & dosage KW - Infusions, Intravenous KW - adverse effects KW - Male KW - Mucopolysaccharidosis I KW - drug therapy KW - Young Adult N1 - Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.ymgme.2008.10.009 ER -