TY  - GEN
AU  - Rosenberger,Georg
AU  - Meien,Stefanie
AU  - Kutsche,Kerstin
TI  - Oncogenic HRAS mutations cause prolonged PI3K signaling in response to epidermal growth factor in fibroblasts of patients with Costello syndrome
SN  - 1098-1004
PY  - 2009///0528
KW  - Abnormalities, Multiple
KW  - genetics
KW  - Cells, Cultured
KW  - Chromones
KW  - pharmacology
KW  - Craniofacial Abnormalities
KW  - Enzyme Inhibitors
KW  - Epidermal Growth Factor
KW  - Failure to Thrive
KW  - pathology
KW  - Fibroblasts
KW  - drug effects
KW  - Guanosine Triphosphate
KW  - metabolism
KW  - Humans
KW  - Immunoblotting
KW  - Intellectual Disability
KW  - MAP Kinase Kinase 1
KW  - MAP Kinase Kinase 2
KW  - Morpholines
KW  - Mutation
KW  - Phosphatidylinositol 3-Kinases
KW  - Phosphoinositide-3 Kinase Inhibitors
KW  - Phosphorylation
KW  - Proto-Oncogene Proteins c-akt
KW  - Proto-Oncogene Proteins p21(ras)
KW  - Signal Transduction
KW  - Skin
KW  - Skin Abnormalities
KW  - Syndrome
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1002/humu.20855
ER  -