TY  - GEN
AU  - Liu,Sijiu
AU  - Zeng,Li-Fan
AU  - Wu,Li
AU  - Yu,Xiao
AU  - Xue,Ting
AU  - Gunawan,Andrea M
AU  - Long,Ya-Qiu
AU  - Zhang,Zhong-Yin
TI  - Targeting inactive enzyme conformation: aryl diketoacid derivatives as a new class of PTP1B inhibitors
SN  - 1520-5126
PY  - 2009///0206
KW  - Amides
KW  - chemistry
KW  - Cell Line, Tumor
KW  - Crystallography, X-Ray
KW  - Dimerization
KW  - Drug Evaluation, Preclinical
KW  - Enzyme Activation
KW  - drug effects
KW  - Enzyme Inhibitors
KW  - chemical synthesis
KW  - Humans
KW  - Keto Acids
KW  - Models, Molecular
KW  - Molecular Structure
KW  - Protein Binding
KW  - Protein Tyrosine Phosphatase, Non-Receptor Type 1
KW  - antagonists & inhibitors
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/ja8068177
ER  -