TY - GEN AU - Takai,A AU - Toyoshima,T AU - Uemura,M AU - Kitawaki,Y AU - Marusawa,H AU - Hiai,H AU - Yamada,S AU - Okazaki,I M AU - Honjo,T AU - Chiba,T AU - Kinoshita,K TI - A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations SN - 1476-5594 PY - 2009///0217 KW - Aging KW - genetics KW - Alkaline Phosphatase KW - Animals KW - Antigens, Differentiation KW - B-Lymphocytes KW - metabolism KW - Carcinoma, Hepatocellular KW - Cytidine Deaminase KW - Disease Models, Animal KW - Embryo, Mammalian KW - Gene Expression Regulation, Neoplastic KW - Genome, Human KW - Hepatitis KW - Humans KW - Liver KW - Liver Neoplasms KW - Mice KW - Mice, Transgenic KW - Organ Specificity KW - Sequence Deletion KW - Somatic Hypermutation, Immunoglobulin KW - Stem Cells KW - Tumor Suppressor Protein p53 KW - alpha-Fetoproteins KW - AICDA (Activation-Induced Cytidine Deaminase) N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/onc.2008.415 ER -