Boadas-Vaello, Pere <br/><br/>
Allylnitrile metabolism by CYP2E1 and other CYPs leads to distinct lethal and vestibulotoxic effects in the mouse.  [electronic resource] 

 -  Toxicological sciences : an official journal of the Society of Toxicology  Feb 2009 
 - 461-72 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1096-0929 
<br/><br/><label>Standard No.: </label>10.1093/toxsci/kfn233  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetone--toxicity<br/>Allyl Compounds--metabolism<br/>Animals<br/>Aryl Hydrocarbon Hydroxylases--chemistry<br/>Behavior, Animal--drug effects<br/>Cyanides--blood<br/>Cytochrome P-450 CYP2A6<br/>Cytochrome P-450 CYP2E1--genetics<br/>Cytochrome P-450 CYP2E1 Inhibitors<br/>Cytochrome P-450 Enzyme Inhibitors<br/>Cytochrome P-450 Enzyme System--genetics<br/>Cytochrome P450 Family 2<br/>Dose-Response Relationship, Drug<br/>Enzyme Inhibitors--pharmacology<br/>Epoxy Compounds--metabolism<br/>Indicators and Reagents<br/>Mice<br/>Mice, Knockout<br/>Nitriles--blood<br/>Solvents<br/>Vestibular Diseases--chemically induced<br/>Vestibular Function Tests<br/>Vestibule, Labyrinth--pathology