Karas-Kuzelicki, N <br/><br/>
Heterozygosity at the TPMT gene locus, augmented by mutated MTHFR gene, predisposes to 6-MP related toxicities in childhood ALL patients.  [electronic resource] 

 -  Leukemia  May 2009 
 - 971-4 p.  digital 
<br/><br/> Publication Type: Letter 
<br/><br/><label>ISSN: </label>1476-5551 
<br/><br/><label>Standard No.: </label>10.1038/leu.2008.317  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Combined Chemotherapy Protocols--therapeutic use<br/>Child<br/>Drug-Related Side Effects and Adverse Reactions<br/>Female<br/>Hematopoietic Stem Cell Transplantation<br/>Heterozygote<br/>Humans<br/>Male<br/>Mercaptopurine--pharmacology<br/>Methylenetetrahydrofolate Reductase (NADPH2)--genetics<br/>Methyltransferases--genetics<br/>Mutation--genetics<br/>Precursor Cell Lymphoblastic Leukemia-Lymphoma--enzymology<br/>Retrospective Studies