Zeng, Zhihong

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML. [electronic resource] - Blood Jun 2009 - 6215-24 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1528-0020

10.1182/blood-2008-05-158311 doi


Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Blotting, Western
Cell Movement--drug effects
Cell Proliferation--drug effects
Cells, Cultured
Chemokine CXCL12--genetics
Chemotaxis--drug effects
Drug Resistance, Neoplasm
Flow Cytometry
Humans
Immunoenzyme Techniques
Leukemia, Experimental--drug therapy
Leukemia, Myeloid, Acute--drug therapy
Mice
Mice, Inbred BALB C
Mutation--genetics
Protein Kinase Inhibitors--pharmacology
Pyridines--pharmacology
Receptors, CXCR4--antagonists & inhibitors
Stromal Cells--drug effects
fms-Like Tyrosine Kinase 3--genetics