TY  - GEN
AU  - Smith,J R
AU  - Clarke,P A
AU  - de Billy,E
AU  - Workman,P
TI  - Silencing the cochaperone CDC37 destabilizes kinase clients and sensitizes cancer cells to HSP90 inhibitors
SN  - 1476-5594
PY  - 2009///0507
KW  - Adenocarcinoma
KW  - metabolism
KW  - Apoptosis
KW  - drug effects
KW  - Benzoquinones
KW  - pharmacology
KW  - Breast Neoplasms
KW  - Cell Cycle Proteins
KW  - antagonists & inhibitors
KW  - Cell Division
KW  - Cell Line, Tumor
KW  - Chaperonins
KW  - Colonic Neoplasms
KW  - Female
KW  - G1 Phase
KW  - Gene Expression Regulation, Neoplastic
KW  - Gene Targeting
KW  - HSP90 Heat-Shock Proteins
KW  - Humans
KW  - Lactams, Macrocyclic
KW  - Male
KW  - Neoplasm Proteins
KW  - Phosphorylation
KW  - Prostatic Neoplasms
KW  - Proteasome Endopeptidase Complex
KW  - Protein Kinases
KW  - Protein Processing, Post-Translational
KW  - Pyrazoles
KW  - RNA Interference
KW  - RNA, Small Interfering
KW  - Signal Transduction
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/onc.2008.380
ER  -