Gu, Hongyan <br/><br/>
Gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells.  [electronic resource] 

 -  Molecular cancer therapeutics  Oct 2008 
 - 3298-305 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1535-7163 
<br/><br/><label>Standard No.: </label>10.1158/1535-7163.MCT-08-0212  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Annexin A5--metabolism<br/>Antineoplastic Agents--pharmacology<br/>Apoptosis--drug effects<br/>Cell Proliferation--drug effects<br/>Down-Regulation--drug effects<br/>Humans<br/>Male<br/>Mice<br/>Mice, Inbred BALB C<br/>Neoplasms--metabolism<br/>Propidium--metabolism<br/>Proto-Oncogene Proteins c-mdm2--genetics<br/>Transcription, Genetic--drug effects<br/>Tumor Suppressor Protein p53--genetics<br/>Up-Regulation--drug effects<br/>Xanthones--chemistry<br/>Xenograft Model Antitumor Assays