Noborio-Hatano, K

Bortezomib overcomes cell-adhesion-mediated drug resistance through downregulation of VLA-4 expression in multiple myeloma. [electronic resource] - Oncogene Jan 2009 - 231-42 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1476-5594

10.1038/onc.2008.385 doi


Antibodies--pharmacology
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Boronic Acids--pharmacology
Bortezomib
Cell Adhesion--physiology
Cell Adhesion Molecules--physiology
Cell Line, Tumor--metabolism
Dexamethasone--pharmacology
Down-Regulation
Doxorubicin--pharmacology
Drug Resistance, Neoplasm--drug effects
Gene Expression Regulation, Neoplastic--drug effects
Gene Knockdown Techniques
Humans
Integrin alpha Chains--biosynthesis
Integrin alpha4--biosynthesis
Integrin alpha4beta1--physiology
Multiple Myeloma--drug therapy
Neoplasm Proteins--biosynthesis
Pyrazines--pharmacology
Vincristine--pharmacology