TY - GEN AU - Sancho,Patricia AU - Bertran,Esther AU - Caja,Laia AU - Carmona-Cuenca,Irene AU - Murillo,Miguel M AU - Fabregat,Isabel TI - The inhibition of the epidermal growth factor (EGF) pathway enhances TGF-beta-induced apoptosis in rat hepatoma cells through inducing oxidative stress coincident with a change in the expression pattern of the NADPH oxidases (NOX) isoforms SN - 0006-3002 PY - 2009///0401 KW - Animals KW - Antioxidants KW - metabolism KW - Apoptosis KW - drug effects KW - Carcinoma, Hepatocellular KW - enzymology KW - Epidermal Growth Factor KW - ErbB Receptors KW - antagonists & inhibitors KW - Gene Expression Regulation, Neoplastic KW - Isoenzymes KW - genetics KW - Liver Neoplasms KW - Mitochondria KW - NADH, NADPH Oxidoreductases KW - NADPH Oxidase 1 KW - NADPH Oxidase 4 KW - NADPH Oxidases KW - Oxidative Stress KW - Protein Kinase Inhibitors KW - pharmacology KW - Quinazolines KW - RNA, Small Interfering KW - Rats KW - Reactive Oxygen Species KW - Transforming Growth Factor beta KW - Tyrphostins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.bbamcr.2008.09.003 ER -