Sancho, Patricia <br/><br/>
The inhibition of the epidermal growth factor (EGF) pathway enhances TGF-beta-induced apoptosis in rat hepatoma cells through inducing oxidative stress coincident with a change in the expression pattern of the NADPH oxidases (NOX) isoforms.  [electronic resource] 

 -  Biochimica et biophysica acta  Feb 2009 
 - 253-63 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0006-3002 
<br/><br/><label>Standard No.: </label>10.1016/j.bbamcr.2008.09.003  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antioxidants--metabolism<br/>Apoptosis--drug effects<br/>Carcinoma, Hepatocellular--enzymology<br/>Epidermal Growth Factor--metabolism<br/>ErbB Receptors--antagonists & inhibitors<br/>Gene Expression Regulation, Neoplastic--drug effects<br/>Isoenzymes--genetics<br/>Liver Neoplasms--enzymology<br/>Mitochondria--drug effects<br/>NADH, NADPH Oxidoreductases--genetics<br/>NADPH Oxidase 1<br/>NADPH Oxidase 4<br/>NADPH Oxidases--genetics<br/>Oxidative Stress--drug effects<br/>Protein Kinase Inhibitors--pharmacology<br/>Quinazolines<br/>RNA, Small Interfering--metabolism<br/>Rats<br/>Reactive Oxygen Species--metabolism<br/>Transforming Growth Factor beta--pharmacology<br/>Tyrphostins--pharmacology