TY  - GEN
AU  - Heemstra,John R
AU  - Walsh,Christopher T
TI  - Tandem action of the O2- and FADH2-dependent halogenases KtzQ and KtzR produce 6,7-dichlorotryptophan for kutzneride assembly
SN  - 1520-5126
PY  - 2009///0128
KW  - Actinobacteria
KW  - metabolism
KW  - Bacterial Proteins
KW  - chemistry
KW  - Chlorides
KW  - Chromatography, High Pressure Liquid
KW  - methods
KW  - Cyclization
KW  - Depsipeptides
KW  - biosynthesis
KW  - Flavin-Adenine Dinucleotide
KW  - analogs & derivatives
KW  - Halogenation
KW  - Molecular Conformation
KW  - Multienzyme Complexes
KW  - Oxidoreductases
KW  - Oxygen
KW  - Stereoisomerism
KW  - Time Factors
KW  - Tryptophan
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1021/ja806467a
ER  -