Heemstra, John R

Tandem action of the O2- and FADH2-dependent halogenases KtzQ and KtzR produce 6,7-dichlorotryptophan for kutzneride assembly. [electronic resource] - Journal of the American Chemical Society Oct 2008 - 14024-5 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1520-5126

10.1021/ja806467a doi


Actinobacteria--metabolism
Bacterial Proteins--chemistry
Chlorides--metabolism
Chromatography, High Pressure Liquid--methods
Cyclization
Depsipeptides--biosynthesis
Flavin-Adenine Dinucleotide--analogs & derivatives
Halogenation
Molecular Conformation
Multienzyme Complexes--chemistry
Oxidoreductases--chemistry
Oxygen--chemistry
Stereoisomerism
Time Factors
Tryptophan--analogs & derivatives