Choonara, Yahya E Mechanistic evaluation of alginate-HEC gelisphere compacts for controlled intrastriatal nicotine release in Parkinson's disease. [electronic resource] - Journal of pharmaceutical sciences Jun 2009 - 2059-72 p. digital Publication Type: Journal Article ISSN: 1520-6017 Standard No.: 10.1002/jps.21590 doi Subjects--Topical Terms: Alginates--chemical synthesisCellulose--analogs & derivativesCross-Linking Reagents--chemical synthesisDrug Delivery Systems--methodsElasticityGels--chemical synthesisGlucuronic Acid--chemical synthesisHexuronic Acids--chemical synthesisHumansNeuroprotective Agents--administration & dosageNicotine--administration & dosageParkinson Disease--drug therapyPhase TransitionSurface PropertiesTime FactorsWater--chemistry