TY  - GEN
AU  - Nassar,Taher
AU  - Rom,Alona
AU  - Nyska,Abraham
AU  - Benita,Simon
TI  - Novel double coated nanocapsules for intestinal delivery and enhanced oral bioavailability of tacrolimus, a P-gp substrate drug
SN  - 1873-4995
PY  - 2009///0217
KW  - ATP Binding Cassette Transporter, Subfamily B, Member 1
KW  - metabolism
KW  - Administration, Oral
KW  - Analysis of Variance
KW  - Animals
KW  - Area Under Curve
KW  - Biological Availability
KW  - Drug Delivery Systems
KW  - methods
KW  - Enterocytes
KW  - Hypromellose Derivatives
KW  - Immunosuppressive Agents
KW  - chemistry
KW  - Intestinal Absorption
KW  - Intestinal Mucosa
KW  - Intestines
KW  - pathology
KW  - Methylcellulose
KW  - analogs & derivatives
KW  - Microscopy, Electron, Scanning
KW  - Microspheres
KW  - Nanocapsules
KW  - Particle Size
KW  - Plant Oils
KW  - Polymethacrylic Acids
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Surface Properties
KW  - Swine
KW  - Tacrolimus
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.jconrel.2008.08.021
ER  -